BDBM50439755 CHEMBL2419438

SMILES CCc1nnc(-c2ccc(cc2)-c2ccccc2)n1-c1cccc(c1C)[N+]([O-])=O

InChI Key InChIKey=NMHFNABMCDUOFJ-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439755   

TargetSodium- and chloride-dependent glycine transporter 2(Rat)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50439755(CHEMBL2419438)Copy SMILESCopy InChI

Affinity DataIC50: 1.30E+4nMAssay Description:Displacement of [3H]glycine from GlyT2 in Wistar rat brainstem cells after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetSodium- and chloride-dependent glycine transporter 1(Rat)
Astellas Pharma

Curated by ChEMBL

LigandBDBM50439755(CHEMBL2419438)Copy SMILESCopy InChI

Affinity DataIC50: 800nMAssay Description:Displacement of [3H]glycine from GlyT1 in rat C6 glioma cells incubated for 30 mins prior to substrate addition measured after 10 mins by scintillati...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/13/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL