BDBM50439801 CHEMBL2419696

SMILES COc1cc(c(cc1C(=O)NCCN2CCC(CC2)C(=O)c3ccc(cc3)F)C#N)Cl

InChI Key InChIKey=LTVIGJUDBNCHPV-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50439801   

TargetProtein Wnt-3a(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439801(CHEMBL2419696)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439801(CHEMBL2419696)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of PARP1 (unknown origin) assessed as nicotinamide concentration by LC-MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed