BDBM50440135 CHEMBL2426395

SMILES COc1ccc(NC(=S)NC(=O)c2cn(nc2-c2ccc(OC)cc2)-c2ccccc2)cc1

InChI Key InChIKey=YECDMWPRVSKSOX-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50440135   

TargetCyclin-dependent kinase 6(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440135(CHEMBL2426395)
Affinity DataIC50: 29nMAssay Description:Inhibition of CDK6 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440135(CHEMBL2426395)
Affinity DataIC50: 522nMAssay Description:Inhibition of CDK1 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 5(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440135(CHEMBL2426395)
Affinity DataIC50: 1.09E+3nMAssay Description:Inhibition of CDK5 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50440135(CHEMBL2426395)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of CDK7 (unknown origin) using histone H1 as substrate after 10 mins in presence of [gamma-32P]-ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed