BDBM50440571 CHEMBL2426474

SMILES O=C(N1CCC(CC1)N1CCCCC1)c1ccc(cc1)C(=O)N1CCC(CC1)N1CCCCC1

InChI Key InChIKey=HOUMUCTZMMLNTR-UHFFFAOYSA-N

Data  19 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50440571   

TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 53BP1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.70E+5nMAssay Description:Inhibition of His-tagged L3MBTL1 (unknown origin) using H4K20Me1 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetMBT domain-containing protein 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of MBTD1 (130 to 566) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me1 as substrate incubated for 30 mins at...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetTP53-binding protein 1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of 53BP1 (1485 to 1611) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H4K20Me2 as substrate incubated for 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase UHRF1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of UHRF1 tandem tudor domain (121 to 286) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H3K9Me3 as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetPHD finger protein 23(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GST-tagged PHF23 (unknown origin) using H3K4Me3 as substrate incubated for 30 mins at room temperature followed by incubation under dar...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of GST-tagged Jarid1A (unknown origin) using H3K4Me3 as substrate incubated for 30 mins at room temperature followed by incubation under d...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetChromobox protein homolog 7(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CBX7 (8 to 62) (unknown origin) expressed in Escherichia coli BL21 Rosetta DE3 using H3K9Me3 as substrate incubated for 30 mins at room...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 3(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of His-tagged L3MBTL3 (unknown origin) using H4K20Me2 as substrate incubated for 30 mins at room temperature followed by incubation under ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetChromobox protein homolog 7(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CBX7 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMBT domain-containing protein 1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of MBTD1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetE3 ubiquitin-protein ligase UHRF1(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of UHRF1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLysine-specific demethylase 5A(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JARID1A (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 4(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L3MBTL4 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetIsoform 4 of Lethal(3)malignant brain tumor-like protein 1 (4)(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L3MBTL1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPHD finger protein 23(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PHF23 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 3(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L3MBTL3 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetLethal(3)malignant brain tumor-like protein 3(Human)
University of North Carolina

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of L3MBTL3 (unknown origin) using H4K20me2 as substrate after 30 mins by LNCE-TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetScm-like with four MBT domains protein 1(Human)
University of North Carolina At Chapel Hill

Curated by ChEMBL
LigandPNGBDBM50440571(CHEMBL2426474)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of SFMBT1 (unknown origin) after 30 mins by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed