BDBM50440937 CHEMBL2431944::US10196373, Compound XW1-057

SMILES Cc1ccc(cc1)S(=O)(=O)N(CC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(C(O)=O)c(O)c1)Cc1ccc(SC(F)(F)F)cc1

InChI Key InChIKey=WLOGUWZVRWDETC-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50440937   

TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50440937(CHEMBL2431944 | US10196373, Compound XW1-057)
Affinity DataIC50: 9.60E+3nMAssay Description:Competitive binding affinity to Stat3 SH2 domain (unknown origin) using 5-FAM-GpYLPQTV-NH2 as probe assessed as phosphopetide complex formation after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50440937(CHEMBL2431944 | US10196373, Compound XW1-057)
Affinity DataKi:  4.80E+3nMAssay Description:ChIP assay was performed using EZ ChIP Kit (Millipore, Billerica, Mass., USA) as per manufacturer's instruction. Briefly, after crosslinking with...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/14/2019
Entry Details
Go to US Patent