BDBM50441413 CHEMBL2435999

SMILES COc1cc2c(Oc3ccc(NC(=O)c4cc(ccn4)-c4ccc(C)cc4)cc3F)ccnc2cc1OCCCN1CCN(C)CC1

InChI Key InChIKey=YEGSATWQBXVWBX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50441413   

TargetPlatelet-derived growth factor receptor beta(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50441413(CHEMBL2435999)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of PDGFRbeta (unknown origin) using poly (Glu, Tyr) (4:1) as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein kinase FLT3(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50441413(CHEMBL2435999)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of FLT3 (unknown origin) using poly (Glu, Tyr) (4:1) as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Key Laboratory of Structure-Based Drug Design and Discovery (Shenyang Pharmaceutical University)

Curated by ChEMBL
LigandPNGBDBM50441413(CHEMBL2435999)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of c-MET (unknown origin) using poly (Glu, Tyr) (4:1) as substrate after 30 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed