BDBM50441702 CHEMBL2435861

SMILES CC(CCNC(=O)c1c(C)cc(Cl)nc1C)N1CCC(CC1)N1[C@@H](CN(Cc2ccccn2)C1=O)c1ccccc1

InChI Key InChIKey=VLCNIWNAFVRZRX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441702   

TargetC-C chemokine receptor type 5(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441702(CHEMBL2435861)
Affinity DataIC50: 2.90nMAssay Description:Antagonist activity at CCR5 (unknown origin) expressed in HEK293F cell membranes assessed as inhibition of RANTES-induced calcium flux preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetC-C chemokine receptor type 5(Human)
Sanofi

Curated by ChEMBL
LigandPNGBDBM50441702(CHEMBL2435861)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of CCR5 (unknown origin) expressed in human HeLa cells assessed as inhibition of interaction of CHO cells expressing HIV-1 JRFLenv and HIV...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed