BDBM50442068 CHEMBL2441057

SMILES Fc1cccc(COc2cccc(NC(=O)C3CCN(CC3)c3ccncc3)c2)c1

InChI Key InChIKey=NTCCWWNRATWWLQ-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50442068   

TargetProthrombin(Bovine)
University of Bari &Quot;Aldo Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProthrombin(Bovine)
University of Bari &Quot;Aldo Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  6nMAssay Description:Inhibition of bovine thrombin using D-Phe-Pip-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
University of Bari &Quot;Aldo Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  5.64E+3nMAssay Description:Inhibition of human factor 10a using Z-D-Arg-Gly-Arg-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetChymotrypsinogen A(Bovine)
University of Bari &Quot;Aldo Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  6.60E+3nMAssay Description:Inhibition of bovine alpha-chymotrypsin using N-succinyl-Ala-Ala-Pro-Phe-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
University of Bari &Quot;Aldo Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi:  1.13E+4nMAssay Description:Inhibition of human neutrophil leukocyte elastase using N-(methoxysuccinyl)-Ala-Ala-Pro-Val-p-NA as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCoagulation factor VII(Human)
University of Bari &Quot;Aldo Moro&Quot

Curated by ChEMBL
LigandPNGBDBM50442068(CHEMBL2441057)
Affinity DataKi: >2.50E+5nMAssay Description:Inhibition of human recombinant factor 7a using spectrozyme as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed