BDBM50442159 CHEMBL2441285

SMILES COc1ccc2c(n1)sc(n2)Nc3cc(nc(n3)NC4CCC(CC4)O)C(c5ccc(cc5)F)(F)F

InChI Key InChIKey=PFDUFECOJKSDAT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442159   

TargetTyrosine-protein kinase ITK/TSK(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50442159(CHEMBL2441285)
Affinity DataKi:  16nMAssay Description:Inhibition of recombinant human FLAG-tagged ITK using biotinylated GST-SAM68 as substrate after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50442159(CHEMBL2441285)
Affinity DataKi: >2.00E+4nMAssay Description:Inhibition of Aurora-B (unknown origin) using 5FAM-PKAtide as substrate after 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed