BDBM50442292 CHEMBL2442249

SMILES CCN1CCN(CC1)C(c1ccc(cc1)C(F)(F)F)c1cc(Cl)c2cccnc2c1O

InChI Key InChIKey=JKUMTZMZMYVTEJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442292   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Eutropics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442292(CHEMBL2442249)
Affinity DataIC50: 310nMAssay Description:Inhibition of human GST-tagged Mcl1 expressed in Escherichia coli BL21 using FITC-AHA-MRPEIWIAQELRRIGDEFNA-[NH2] after 20 mins by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Eutropics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442292(CHEMBL2442249)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human GST-tagged Bcl-xL expressed in Escherichia coli BL21 using FITC-AHA-MRPEIWIAQELRRIGDEFNA-[NH2] after 20 mins by fluorescence pola...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed