BDBM50442297 CHEMBL2442244

SMILES Oc1c(cc(Cl)c2cccnc12)C(Nc1ccccn1)c1ccccc1F

InChI Key InChIKey=CWNKFDCPRPBCRF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442297   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Eutropics Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50442297(CHEMBL2442244)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human GST-tagged Mcl1 expressed in Escherichia coli BL21 using FITC-AHA-MRPEIWIAQELRRIGDEFNA-[NH2] after 20 mins by fluorescence polari...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBotulinum neurotoxin type A(Clostridium botulinum)
U.S. Army Medical Research Institute of Infectious Diseases

Curated by ChEMBL
LigandPNGBDBM50442297(CHEMBL2442244)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of protease activity of recombinant full length Clostridium botulinum Hall BoNT/A light chain using SNAP-25 peptide (187 to 203 residues) ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/13/2019
Entry Details Article
PubMed