BDBM50442320 CHEMBL2442762

SMILES CCn1ccc2c1ccc1nc(cc(Cn3cncn3)c21)-c1ccccc1

InChI Key InChIKey=CFSABHQRTGUEMV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50442320   

TargetAromatase(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50442320(CHEMBL2442762)
Affinity DataIC50: 13nMAssay Description:Inhibition of aromatase (unknown origin) using 7-methoxy-4-trifluoromethylcoumarin as substrate after 30 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50442320(CHEMBL2442762)
Affinity DataIC50: 1.48E+3nMAssay Description:Inhibition of human CYP11B1 using [1,2-3H]-11-deoxycorticosterone as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
University of Padova

Curated by ChEMBL
LigandPNGBDBM50442320(CHEMBL2442762)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human CYP17 expressed in Escherichia coli using progesterone as substrate NADPH as cofactorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed