BDBM50442535 CHEMBL2440126

SMILES CCOC(=O)C(NO)C=N[C@H]1C[C@@]2(C)[C@@H](CC[C@@H]2C(C)=O)[C@@H]2CCC3=CC(=O)CC[C@]3(C)[C@@H]12

InChI Key InChIKey=GWKNZAIXTHYDEV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442535   

Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50442535(CHEMBL2440126)
Affinity DataIC50: 640nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in HEK293 cells assessed as inhibition of [1,2,-3H]-cortisone to [3H]cortisol preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase type 2(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50442535(CHEMBL2440126)
Affinity DataIC50: 1.05E+3nMAssay Description:Inhibition of human recombinant 11beta-HSD2 expressed in HEK293 cells assessed as inhibition of [1,2,6,7-3H]-cortisol to [3H]cortisone preincubated f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed