BDBM50443122 CHEMBL3086314::US8674100, 27

SMILES CC1(C)CCC(=CC1)c1cc(CCS(=O)(=O)N2CCOCC2)ccc1NC(=O)c1ncc([nH]1)C#N

InChI Key InChIKey=MFJFMWVERXJFRJ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443122   

TargetMacrophage colony-stimulating factor 1 receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50443122(CHEMBL3086314 | US8674100, 27)
Affinity DataIC50: 4.5nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443122(CHEMBL3086314 | US8674100, 27)
Affinity DataIC50: 4.5nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2014
Entry Details
US Patent

TargetMacrophage colony-stimulating factor 1 receptor(Mouse)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50443122(CHEMBL3086314 | US8674100, 27)
Affinity DataIC50: 60nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed