BDBM50443389 CHEMBL2376441

SMILES CCCCCc1ccc(\C=C\[C@H](O)[C@@H](CO)NC)cc1

InChI Key InChIKey=JYEXUQKROPHSEF-UHFFFAOYSA-N

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50443389   

TargetSphingosine kinase 2(Human)
Penn State Hershey Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)
Affinity DataIC50: 1.00E+4nMAssay Description:Competitive inhibition of V5-His-tagged human SphK2 expressed in HEK293 cells assessed as S1P production using sphingosine and [gamma-32P]ATP as subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of human recombinant SphK1 expressed in Sf9 cells assessed as radiolabeled products using 5 uM sphingosine and 10 uM gamma[32P]ATP by liqu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of sphingosine kinase 1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSphingosine kinase 1(Human)
Virginia Tech

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)
Affinity DataKi:  1.00E+4nMAssay Description:Inhibition of V5-His-tagged human SphK1 using sphingosine as substrate in presence of [gamma-32P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/30/2020
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Penn State Hershey Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50443389(CHEMBL2376441)
Affinity DataKi: >1.00E+5nMAssay Description:Inhibition of human recombinant SphK2 expressed in Sf9 cells assessed as radiolabeled products using 10 uM sphingosine and 10 uM gamma[32P]ATP by liq...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/25/2016
Entry Details Article
PubMed