BDBM50443527 CHEMBL1339340::acs.jmedchem.1c00409_ST.358::jm5b01461, Compound 180

SMILES Cc1ccc2nc(sc2c1S(O)(=O)=O)-c1ccc(N)cc1

InChI Key InChIKey=KGZUHYIHYBDNLC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50443527   

TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM50443527(CHEMBL1339340 | jm5b01461, Compound 180 | acs.jmed...)
Affinity DataIC50: 4.30E+3nMAssay Description:This is a review article.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/7/2020
Entry Details Article
PubMed
TargetReplicase polyprotein 1ab(SARS-CoV)
University of Bonn

LigandPNGBDBM50443527(CHEMBL1339340 | jm5b01461, Compound 180 | acs.jmed...)
Affinity DataIC50: 4.30E+3nMAssay Description:This is a review article. Please point to the original journal.More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/27/2022
Entry Details Article
PubMed
Target5'-nucleotidase(Human)
Comsats Institute of Information Technology

Curated by ChEMBL
LigandPNGBDBM50443527(CHEMBL1339340 | jm5b01461, Compound 180 | acs.jmed...)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of human recombinant ecto-5'-nucleotidase expressed in african green monkey COS7 cells using adenosine monophosphate as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
Target5'-nucleotidase(Rat)
Comsats Institute of Information Technology

Curated by ChEMBL
LigandPNGBDBM50443527(CHEMBL1339340 | jm5b01461, Compound 180 | acs.jmed...)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of rat recombinant ecto-5'-nucleotidase expressed in african green monkey COS7 cells using adenosine monophosphate as substrate preincubat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed