BDBM50443649 CHEMBL3093075

SMILES Fc1ccccc1[C@H](Nc1nnc(o1)-c1c[nH]c2ncccc12)C1CC1

InChI Key InChIKey=YFZAJIBGNYMWBT-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50443649   

LigandPNGBDBM50443649(CHEMBL3093075)
Affinity DataIC50: 0.850nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50443649(CHEMBL3093075)
Affinity DataIC50: 31nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using 4eBP1 ULight peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50443649(CHEMBL3093075)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50443649(CHEMBL3093075)
Affinity DataIC50: 240nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) using ULight peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
LigandPNGBDBM50443649(CHEMBL3093075)
Affinity DataIC50: 20nMAssay Description:Inhibition of Cdc7-mediated MCM2 phosphorylation at Ser53 in human HCT116 cells after 14 hrs by immunostaining assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed