BDBM50443732 CHEMBL3093908

SMILES N[C@@H](Cc1ccc(cc1)C(F)(F)F)C(=O)N1C[C@@H](F)C[C@H]1C#N

InChI Key InChIKey=MEPRZPLBMXAVKQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443732   

TargetDipeptidyl peptidase 8(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50443732(CHEMBL3093908)
Affinity DataIC50: 240nMAssay Description:Inhibition of 6xHis-tagged recombinant DPP8 (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Ala-Pro-aminomethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50443732(CHEMBL3093908)
Affinity DataIC50: 610nMAssay Description:Inhibition of 6xHis-tagged recombinant FAP (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Nle-Pro-aminomethylc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDipeptidyl peptidase 9(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50443732(CHEMBL3093908)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of 6xHis-tagged recombinant DPP9 (unknown origin) expressed in baculovirus expression system assessed as hydrolysis of Ala-Pro-aminomethyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed