BDBM50444524 CHEMBL3099814

SMILES N[C@H]1CC[C@@H](CC1)NC(=O)c1ccc(Oc2ccc(cc2)C(N)=N)nc1Oc1ccc(cc1)C(N)=N

InChI Key InChIKey=KGURYHSVQMMONJ-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444524   

TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444524(CHEMBL3099814)
Affinity DataKi:  500nMAssay Description:Inhibition of matriptase-SP1 (615 to 855) (unknown origin) expressed in Escherichia coli BL21(DE3) using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444524(CHEMBL3099814)
Affinity DataKi:  600nMAssay Description:Inhibition of factor 10a (unknown origin) using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444524(CHEMBL3099814)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of thrombin (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444524(CHEMBL3099814)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of uPA (unknown origin) using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed