BDBM50444528 CHEMBL3099589

SMILES [H]/N=C(\c1ccc(cc1)Oc2ccc(c(n2)Oc3ccc(cc3)/C(=N\[H])/N)NS(=O)(=O)c4ccc(cc4)F)/N

InChI Key InChIKey=CVYPHGJZNLYSHQ-UHFFFAOYSA-N

Data  4 KI

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444528   

TargetSuppressor of tumorigenicity 14 protein(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444528(CHEMBL3099589)
Affinity DataKi:  200nMAssay Description:Inhibition of matriptase-SP1 (615 to 855) (unknown origin) expressed in Escherichia coli BL21(DE3) using Boc-Gln-Ala-Arg-7-amido-4-methyl coumarin hy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444528(CHEMBL3099589)
Affinity DataKi:  300nMAssay Description:Inhibition of factor 10a (unknown origin) using CH3OCO-D-CHA-Gly-Arg-pNA.AcoH as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProthrombin(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444528(CHEMBL3099589)
Affinity DataKi:  4.10E+3nMAssay Description:Inhibition of thrombin (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetUrokinase-type plasminogen activator(Human)
Aurigene Discovery Technologies

Curated by ChEMBL
LigandPNGBDBM50444528(CHEMBL3099589)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of uPA (unknown origin) using L-PyroGlu-Gly-Arg-pNA.HCl as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed