BDBM50444781 CHEMBL3099118

SMILES Cc1c(Cc2ccccc2S(=O)(=O)c2ccc(F)cc2)c(nn1CC(O)=O)-c1ccccc1

InChI Key InChIKey=MPJHIEDOYLRDLS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50444781   

TargetProstaglandin D2 receptor 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50444781(CHEMBL3099118)
Affinity DataIC50: 4nMAssay Description:Antagonist activity at CRTh2 in human RBC assessed as inhibition of PGD2-induced eosinophil shape changeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50444781(CHEMBL3099118)
Affinity DataIC50: 70nMAssay Description:Antagonist activity at CRTh2 (unknown origin) expressed in CHO.K1 cells assessed as inhibition of PGD2-induced [35S]-GTPgammaS binding after 2 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50444781(CHEMBL3099118)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at CRTh2 (unknown origin) expressed in CHO.K1 cells assessed as inhibition of PGD2-induced [35S]-GTPgammaS binding after 2 hrs by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProstaglandin D2 receptor 2(Human)
RhôNe-Poulenc Rorer

Curated by ChEMBL
LigandPNGBDBM50444781(CHEMBL3099118)
Affinity DataIC50: 50nMAssay Description:Antagonist activity at CRTh2 in human whole blood assessed as inhibition of PGD2-induced eosinophil shape changeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed