BDBM50444898 CHEMBL3099625

SMILES [#6](-[#6]-[#7]-1-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-1)-[#8]-c1ccc(cc1)-[#6](=[#6]-1/[#6]-[#6]-[#6]-[#6]-[#6]-1)\c1ccc(-[#8]-[#6]-[#6]-[#7]-2-[#6]-[#6]-[#6]-[#6]-[#6]-[#6]-2)cc1

InChI Key InChIKey=ABDUJESVFIIJHA-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50444898   

TargetProteasome subunit beta type-5(Human)
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444898(CHEMBL3099625)
Affinity DataIC50: 2.19E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human 20S proteasome beta 5 subunit assessed as hydrolysis of succinyl-LLVY-AMC fluorogenic substrate mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444898(CHEMBL3099625)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of trypsin-like activity of human 20S proteasome beta 2 subunit assessed as hydrolysis of Boc-LRR-AMC fluorogenic substrate measured for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
Institute of Bio-Science and Technology

Curated by ChEMBL
LigandPNGBDBM50444898(CHEMBL3099625)
Affinity DataIC50: 890nMAssay Description:Inhibition of PGPH-like activity of human 20S proteasome beta 1 subunit assessed as hydrolysis of Z-LLE-AMC fluorogenic substrate measured for 1 hr b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed