BDBM50445002 CHEMBL3099947

SMILES O[C@H](COc1cc(O)ccc1NC(=O)NC1CC1)CN1CCC2(Cc3cc(F)ccc3O2)CC1

InChI Key InChIKey=PYPUGVATTLSFNC-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50445002   

TargetMacrophage inflammatory protein-1 alpha receptor(Rat)
Astrazeneca

Curated by ChEMBL

LigandBDBM50445002(CHEMBL3099947)Copy SMILESCopy InChI

Affinity DataIC50: 101nMAssay Description:Displacement of [125I]MIP-1alpha from rat CCR1More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy Entry DOIPubMed
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TargetC-C chemokine receptor type 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50445002(CHEMBL3099947)Copy SMILESCopy InChI

Affinity DataIC50: 0.630nMAssay Description:Displacement of [125I]MIP-1alpha from human recombinant CCR1 expressed in HEK293 cell membranes after 1.5 hrs by microbeta counting analysisMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/25/2014
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL