BDBM50445476 CHEMBL3104857

SMILES OCC[C@@H]1CN(CC2CCCCC2)CCN1Cc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=HYJVYRBGCPGOSX-UHFFFAOYSA-N

Data  8 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50445476   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Greifswald

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Greifswald

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  7.80nMAssay Description:Binding affinity to sigma 1 receptor expressed in guinea pig brainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Greifswald

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  7.80nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain cortex membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Greifswald

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human RPMI8226 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Greifswald

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  29nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) expressed in human RPMI-8226 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Greifswald

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in human RPMI8226 cell membranes after 120 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2015
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Rat)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  38nMAssay Description:Binding affinity to sigma 2 receptor expressed in rat liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma intracellular receptor 2(Human)
University of Catania

Curated by ChEMBL
LigandPNGBDBM50445476(CHEMBL3104857)
Affinity DataKi:  39nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) expressed in human RT-4 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed