BDBM50446013 CHEMBL3103334

SMILES Brc1ccc(nc1)N1CCN(CC1)C(=O)N1CCOCC1

InChI Key InChIKey=GSDQFDQHPRPTMW-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50446013   

TargetAldo-keto reductase family 1 member C3(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446013(CHEMBL3103334)
Affinity DataIC50: 31nMAssay Description:Inhibition of AKR1C3 (unknown origin) expressed in human HCT116 cells assessed as formation of PR-104H from PR-104A preincubated for 2 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C4(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446013(CHEMBL3103334)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant AKR1C4 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C3(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446013(CHEMBL3103334)
Affinity DataIC50: 100nMAssay Description:Inhibition of recombinant AKR1C3 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C2(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446013(CHEMBL3103334)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant AKR1C2 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAldo-keto reductase family 1 member C1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50446013(CHEMBL3103334)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant AKR1C1 (unknown origin) after 1 hr by competitive fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed