BDBM50446285 CHEMBL3109233

SMILES CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc3n(CCc4ccccc4C(F)(F)F)ccc3c2)cc1

InChI Key InChIKey=FYTYZASBWDBYDY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50446285   

TargetNuclear receptor ROR-gamma(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50446285(CHEMBL3109233)
Affinity DataIC50: 6nMAssay Description:Inverse agonist activity at biotinylated human RORgammat LBD expressed in Escherichia coli BL21 assessed as inhibition of SRC1 recruitment after 1 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed