BDBM50446468 CHEMBL3109954

SMILES CCOc1ccccc1Nc1cc2[nH]c(cc2cn1)-c1cn[nH]c1

InChI Key InChIKey=BEUXYMIIIBPCKC-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50446468   

TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50446468(CHEMBL3109954)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of full length CDK2/Cyclin A (unknown origin) using 5FAMQSPKKG-CONH2 as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50446468(CHEMBL3109954)
Affinity DataIC50: 8.50E+3nMAssay Description:Inhibition of N-terminal His-tagged Aurora A (unknown origin) using 5FAM-LRRASLG-CONH2 as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetDual specificity protein kinase TTK(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50446468(CHEMBL3109954)
Affinity DataIC50: 58nMAssay Description:Inhibition of N-terminal 6XHis-tagged/GST-tagged full length human MPS1 expressed in recombinant baculovirus infected sf9 insect cells using 5FAM-DHT...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50446468(CHEMBL3109954)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of full length Aurora B (unknown origin) using 5FAM-LRRASLG-CONH2 as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Shaanxi University of Science & Technology

Curated by ChEMBL
LigandPNGBDBM50446468(CHEMBL3109954)
Affinity DataIC50: 8.90E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed
TargetAurora kinase A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50446468(CHEMBL3109954)
Affinity DataIC50: 8.50E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed