BDBM50447178 CHEMBL1596118::US10752581, Compound 1

SMILES COc1cccc(CNc2ccc(cc2)S(=O)(=O)Nc2nccs2)c1O

InChI Key InChIKey=CENSVXZQMJBVHY-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50447178   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human 5-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15B(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human epithelial 15-LOX2 using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of N-terminal His6-tagged human reticulocyte 15-LOX1 using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged human platelet 12-LOX using arachidonic acid as substrate by UV-vis spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50447178(CHEMBL1596118 | US10752581, Compound 1)
Affinity DataIC50: 5.10E+3nMAssay Description:UV-vis cuvette-based assay.More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/11/2021
Entry Details
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