BDBM50447509 CHEMBL3115407

SMILES Cc1ccccc1NC(=O)Nc1ccc(CNC(=O)[C@H]2CCN(C2)C(=O)[C@H](CC(O)=O)NC(=O)Cc2ccccc2)cc1

InChI Key InChIKey=HAQDQKGZJSHMBY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50447509   

TargetIntegrin alpha-V/beta-3(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50447509(CHEMBL3115407)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human alphavbeta3 integrin expressed in human SK-MEL-24 cells assessed as inhibition of cell adhesion to vitronectinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50447509(CHEMBL3115407)
Affinity DataIC50: 100nMAssay Description:Displacement of [125I]-FN from human alpha4beta1 integrin expressed in human Jurkat cells by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetIntegrin alpha-4/beta-1(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50447509(CHEMBL3115407)
Affinity DataIC50: 80nMAssay Description:Inhibition of human alpha4beta1 integrin expressed in human Jurkat cells assessed as inhibition of cell adhesion to VCAM-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed