BDBM50447539 CHEMBL3116158

SMILES FC(F)C(F)(F)Oc1cc(F)cc(c1)[C@@](Cc1ccccc1)(Nc1nc(cs1)C(F)(F)F)c1ccc(Cl)cn1

InChI Key InChIKey=CEQKVTUACFLLOZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50447539   

TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50447539(CHEMBL3116158)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant CETP using [3H]-CE/HDL by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50447539(CHEMBL3116158)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50447539(CHEMBL3116158)
Affinity DataIC50: 1.48E+4nMAssay Description:Inhibition of CETP in human whole plasma using [3H]-CE/HDL after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50447539(CHEMBL3116158)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50447539(CHEMBL3116158)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50447539(CHEMBL3116158)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed