BDBM50447879 CHEMBL3114765

SMILES Fc1cc(ccn1)N1CC(C1)c1cccc(NC2=C(C(=O)NC2=O)c2c[nH]c3ccccc23)c1

InChI Key InChIKey=UVKZQVCPVZXPHH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50447879   

TargetTyrosine-protein kinase JAK3(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447879(CHEMBL3114765)
Affinity DataIC50: 576nMAssay Description:Inhibition of JAK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447879(CHEMBL3114765)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Fox Chase Chemical Diversity Center

Curated by ChEMBL
LigandPNGBDBM50447879(CHEMBL3114765)
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed