BDBM50448111 CHEMBL3122116

SMILES CNc1nc(Nc2cn(nc2C)[C@H]2CCN(C[C@H]2F)C2COC2)ncc1C(F)(F)F

InChI Key InChIKey=WQELVDRHGRUOCD-UHFFFAOYSA-N

Data  1 KI  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448111   

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50448111(CHEMBL3122116)Copy SMILESCopy InChI

Affinity DataKi:  2nMAssay Description:Inhibition of LRRK2 (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/26/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetLeucine-rich repeat serine/threonine-protein kinase 2(Human)
Genentech

Curated by ChEMBL

LigandBDBM50448111(CHEMBL3122116)Copy SMILESCopy InChI

Affinity DataIC50: 14nMAssay Description:Inhibition of LRRK2 (unknown origin) phosphorylation by cell-based assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/26/2014
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL