BDBM50448294 CHEMBL3121096

SMILES O=C1NN=C([C@@H]2C[C@H]12)c1ccc(OC2CCN(CC2)C2CCC2)cc1

InChI Key InChIKey=GWVIOFUJTJGECV-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50448294   

TargetHistamine H3 receptor(Rat)
Teva Pharmaceutical Global R & D

Curated by ChEMBL
LigandPNGBDBM50448294(CHEMBL3121096)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]NAMH from rat histamine H3 receptor transfected in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Teva Pharmaceutical Global R & D

Curated by ChEMBL
LigandPNGBDBM50448294(CHEMBL3121096)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Teva Pharmaceutical Global R & D

Curated by ChEMBL
LigandPNGBDBM50448294(CHEMBL3121096)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Teva Pharmaceutical Global R & D

Curated by ChEMBL
LigandPNGBDBM50448294(CHEMBL3121096)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Teva Pharmaceutical Global R & D

Curated by ChEMBL
LigandPNGBDBM50448294(CHEMBL3121096)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed