BDBM50448340 CHEMBL3121455

SMILES COc1cc(cc(OC)c1OC)N(CC#C)Cc1nc2cc(ccc2nc1-c1ccccc1)C(F)(F)F

InChI Key InChIKey=VPYAHWFMTPEBGT-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448340   

TargetDihydrofolate reductase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50448340(CHEMBL3121455)
Affinity DataKi:  4.00E+3nMAssay Description:Competitive inhibition of human dihydrofolate reductase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of Sassari

Curated by ChEMBL
LigandPNGBDBM50448340(CHEMBL3121455)
Affinity DataKi:  5.00E+3nMAssay Description:Competitive inhibition of human thymidylate synthase by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed