BDBM50448462 CHEMBL3126369

SMILES CC(C)c1cc(Cn2ccc3c(NC(=O)C(O)=O)ccc(C)c23)ccc1O

InChI Key InChIKey=QOWDVYZPDZEOEA-UHFFFAOYSA-N

Data  2 IC50  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50448462   

TargetThyroid hormone receptor beta(Human)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50448462(CHEMBL3126369)
Affinity DataIC50: 54nMAssay Description:Displacement of [125I]-Triiodothyronine from human recombinant TRbeta1 ligand binding domain after 2 to 3 hrs by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetThyroid hormone receptor alpha(Human)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50448462(CHEMBL3126369)
Affinity DataIC50: 190nMAssay Description:Displacement of [125I]-Triiodothyronine from human recombinant TRalpha1 ligand binding domain after 2 to 3 hrs by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50448462(CHEMBL3126369)
Affinity DataEC50:  190nMAssay Description:Agonist activity at human recombinant TRbeta1 transfected in human HepG2 cells after 8 to 10 hrs by alkaline phosphatase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Sanwa Kagaku Kenkyusho

Curated by ChEMBL
LigandPNGBDBM50448462(CHEMBL3126369)
Affinity DataEC50:  500nMAssay Description:Agonist activity at human recombinant TRbeta1 transfected in CV-1 cells after 8 to 10 hrs by alkaline phosphatase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed