BDBM50448652 CHEMBL3127536

SMILES Fc1ccc2CCN(C3CCN(CC3)c3ccc(nn3)-c3ccc(nc3)C(F)(F)F)c2c1

InChI Key InChIKey=RHBTVSAJSUTJRD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448652   

TargetStearoyl-CoA desaturase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50448652(CHEMBL3127536)
Affinity DataIC50: 14nMAssay Description:Inhibition of SCD1 in human A431 cells assessed as [13C]-palmitic acid conversion to [13C]-palmitoleic acid after 4 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50448652(CHEMBL3127536)
Affinity DataIC50: 16nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using stearoyl-[9,10-3H]-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed