BDBM50448672 CHEMBL3127542

SMILES Cc1cn(cn1)-c1ccc(nn1)N1CCC(CC1)N1CCc2ccc(F)cc12

InChI Key InChIKey=IPTWJKSNCXVPQK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448672   

TargetStearoyl-CoA desaturase(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50448672(CHEMBL3127542)
Affinity DataIC50: 9nMAssay Description:Inhibition of SCD1 in human A431 cells assessed as [13C]-palmitic acid conversion to [13C]-palmitoleic acid after 4 hrs by LC/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetAcyl-CoA desaturase 1(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50448672(CHEMBL3127542)
Affinity DataIC50: 16nMAssay Description:Inhibition of SCD1 in Sprague-Dawley rat liver microsomes using stearoyl-[9,10-3H]-CoA as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed