BDBM50449051 CHEMBL3126485

SMILES CN(C)CCCn1c(=O)c2ccc3c4ccc5c6c(ccc(c7ccc(c2c37)c1=O)c46)c(=O)n(CCCN(C)C)c5=O

InChI Key InChIKey=ASCSVRAUWKNNCO-UHFFFAOYSA-N

Data  12 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50449051   

TargetHypoxia-inducible factor 1-alpha(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human MDA-MB-468 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human MDA-MB-231 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human OVCAR3 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetHypoxia-inducible factor 1-alpha(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of HIF-1 alpha in human PANC1 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-468 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-468 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-231 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human PANC1 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human PANC1 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human OVCAR3 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human OVCAR3 cells by Western blotting analysis in hypoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Baylor College of Medicine

Curated by ChEMBL
LigandPNGBDBM50449051(CHEMBL3126485)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of Stat3 phosphorylation in human MDA-MB-231 cells by Western blotting analysis in normoxia conditionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed