BDBM50449369 CHEMBL3126333

SMILES C=Cc1ccc(c(c1)NS(=O)(=O)c2ccccc2)C(=O)O

InChI Key InChIKey=SWCRJSPSKPQDKL-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449369   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Research & Development, Abbvie

Curated by ChEMBL
LigandPNGBDBM50449369(CHEMBL3126333)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant MCL-1 (174 to 236) expressed in Escherichia coli BL21(DE3) using 6FAM-GELEVEFATQLRRFGDKLN as substrate after 15 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Research & Development, Abbvie

Curated by ChEMBL
LigandPNGBDBM50449369(CHEMBL3126333)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of Mcl1 (unknown origin) by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)