BDBM50449651 CHEMBL4172818

SMILES Nc1nc(NCc2cnccn2)nc2sc(nc12)-c1ccco1

InChI Key InChIKey=NHUDWRIFKGAOEZ-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50449651   

TargetAdenosine receptor A2a(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50449651(CHEMBL4172818)
Affinity DataKi:  5.10nMAssay Description:Displacement of [3H]ZM241385 from human adenosine A2A receptor expressed in CHO cell membranes measured after 60 mins by scintillation counting metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50449651(CHEMBL4172818)
Affinity DataIC50: 8.30nMAssay Description:Inverse agonist activity at human adenosine A2A receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2a(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50449651(CHEMBL4172818)
Affinity DataIC50: 11nMAssay Description:Antagonist activity against human adenosine A2A receptor expressed in CHO cells assessed as inhibition of CGS21680-stimulated cAMP accumulation measu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A2b(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50449651(CHEMBL4172818)
Affinity DataIC50: 13nMAssay Description:Inverse agonist activity at human adenosine A2B receptor expressed in CHO cells assessed as inhibition of cAMP accumulation measured after 150 mins i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A1(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50449651(CHEMBL4172818)
Affinity DataKi:  25nMAssay Description:Displacement of [3H]DPCPX from human adenosine A1 receptor expressed in CHO cell membranes measured after 90 mins by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAdenosine receptor A3(Human)
Universita Degli Studi Di Firenze

Curated by ChEMBL
LigandPNGBDBM50449651(CHEMBL4172818)
Affinity DataKi:  157nMAssay Description:Displacement of [125I]AB-MECA from human adenosine A3 receptor expressed in CHO cell membranes measured after 120 mins by scintillation counting meth...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed