BDBM50449699 CHEMBL4166294

SMILES Cc1cc(C)nc(SCC(=O)Nc2cccc(COc3cccc(NC(=O)c4cccs4)c3)c2)n1

InChI Key InChIKey=MBOZUBLEJCOXTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449699   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
West China School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50449699(CHEMBL4166294)
Affinity DataIC50: 1.28E+5nMAssay Description:Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
West China School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50449699(CHEMBL4166294)
Affinity DataIC50: 1.29E+5nMAssay Description:Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed