BDBM50449701 CHEMBL4171455

SMILES Cc1cc(C)nc(SCC(=O)Nc2cccc(COc3ccc(NC(=O)C4CCCN4)cc3)c2)n1

InChI Key InChIKey=ZNYWGMBLRULQHE-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50449701   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
West China School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50449701(CHEMBL4171455)
Affinity DataIC50: 4.13E+4nMAssay Description:Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
West China School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50449701(CHEMBL4171455)
Affinity DataIC50: 4.17E+4nMAssay Description:Inhibition of recombinant His-tagged SIRT2 (56 to 356 residues) (unknown origin) expressed in Escherichia coli Transetta(DE3) using AcIQF as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed