BDBM50449738 CHEMBL4174958

SMILES Nc1c2CCCCc2nc2NC(=S)NC(c3cccc(Br)c3)c12

InChI Key InChIKey=RTYBGCWRXWDNEV-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50449738   

TargetAcetylcholinesterase(Human)
Laboratory of Medicinal Chemistry (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50449738(CHEMBL4174958)
Affinity DataIC50: 37nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine as substrate pretreated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Laboratory of Medicinal Chemistry (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50449738(CHEMBL4174958)
Affinity DataKi:  147nMAssay Description:Non-competitive inhibition of recombinant human AChE expressed in HEK293 cells assessed as enzyme-substrate-inhibitor complex using varying levels of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Laboratory of Medicinal Chemistry (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50449738(CHEMBL4174958)
Affinity DataIC50: 1.27E+3nMAssay Description:Inhibition of recombinant human serum BChE using butyrylthiocholine as substrate pretreated for 20 mins followed by substrate addition by Ellman's me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed