BDBM50449745 CHEMBL4171520

SMILES COc1cccc(c1)C1NC(=S)Nc2nc3CCCCc3c(N)c12

InChI Key InChIKey=GLVAOWPNTIXLJA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50449745   

TargetAcetylcholinesterase(Human)
Laboratory of Medicinal Chemistry (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50449745(CHEMBL4171520)
Affinity DataIC50: 3.05E+3nMAssay Description:Inhibition of recombinant human AChE expressed in HEK293 cells using acetylthiocholine as substrate pretreated for 20 mins followed by substrate addi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCholinesterase(Human)
Laboratory of Medicinal Chemistry (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50449745(CHEMBL4171520)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of recombinant human serum BChE using butyrylthiocholine as substrate pretreated for 20 mins followed by substrate addition by Ellman's me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetAcetylcholinesterase(Human)
Laboratory of Medicinal Chemistry (Iqog, Csic)

Curated by ChEMBL
LigandPNGBDBM50449745(CHEMBL4171520)
Affinity DataKi:  3.88E+3nMAssay Description:Non-competitive inhibition of recombinant human AChE expressed in HEK293 cells assessed as enzyme-substrate-inhibitor complex using varying levels of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed