BDBM5045 Methyl 2-{[(5-tert-butyl-3,4-dimethyl-1,3-thiazol-2(3H)-ylidene)amino]sulfonyl}-4-chlorobenzoate::methyl 2-{[(2Z)-5-tert-butyl-3,4-dimethyl-2,3-dihydro-1,3-thiazol-2-ylidene]sulfamoyl}-4-chlorobenzoate::thiazolidenebenzenesulfonamide deriv. 16

SMILES COC(=O)c1ccc(Cl)cc1S(=O)(=O)\N=c1/sc(c(C)n1C)C(C)(C)C

InChI Key InChIKey=BKXXZGMFIHVMRS-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5045   

TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5045(methyl 2-{[(2Z)-5-tert-butyl-3,4-dimethyl-2,3-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1027,K690N]/[588-1147,K690N](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5045(methyl 2-{[(2Z)-5-tert-butyl-3,4-dimethyl-2,3-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2005
Entry Details Article
PubMed
TargetGag-Pol polyprotein [588-1127,Y768C]/[588-1147,Y768C](Human immunodeficiency virus type 1)
Yamanouchi Pharmaceutical

LigandPNGBDBM5045(methyl 2-{[(2Z)-5-tert-butyl-3,4-dimethyl-2,3-dihy...)
Affinity DataIC50: 1.00E+4nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2005
Entry Details Article
PubMed