BDBM50450079 CHEMBL4166976
SMILES O=c1cc([nH]c2nc(SCc3nc4ccccc4[nH]3)nn12)-c1ccccc1
InChI Key InChIKey=KDTKXHZGLKGSRG-UHFFFAOYSA-N
Data 19 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 19 hits for monomerid = 50450079
Affinity DataIC50: 30nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel I...More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel I...More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel I...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin...More data for this Ligand-Target Pair
Affinity DataIC50: 290nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin...More data for this Ligand-Target Pair
Affinity DataIC50: 380nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin...More data for this Ligand-Target Pair
Affinity DataIC50: 660nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 20 uM afte...More data for this Ligand-Target Pair
Affinity DataIC50: 800nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 20 uM af...More data for this Ligand-Target Pair
Affinity DataIC50: 830nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 4 uM after...More data for this Ligand-Target Pair
Affinity DataIC50: 920nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 4 uM aft...More data for this Ligand-Target Pair
Affinity DataIC50: 1.28E+3nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of doxorubicin-induced cytotoxicity by measuring doxorubicin IC50 at 10 uM af...More data for this Ligand-Target Pair
Affinity DataIC50: 1.47E+3nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 10 uM afte...More data for this Ligand-Target Pair
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 10 uM after ...More data for this Ligand-Target Pair
Affinity DataIC50: 1.59E+3nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 4 uM after 7...More data for this Ligand-Target Pair
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of ABCB1 in human SW620/Ad300 cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC50 at 20 uM after ...More data for this Ligand-Target Pair
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC5...More data for this Ligand-Target Pair
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC5...More data for this Ligand-Target Pair
Affinity DataIC50: 8.26E+3nMAssay Description:Inhibition of ABCB1 (unknown origin) expressed in HEK293T cells assessed as potentiation of cisplatin-induced cytotoxicity by measuring cisplatin IC5...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+5nMAssay Description:Inhibition of ABCB1 in multidrug-resistant human SW620/Ad300 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity ...More data for this Ligand-Target Pair