BDBM50450083 CHEMBL4166588

SMILES Nc1ncnc2n(CCNCCN=Cc3ccc(O)cc3O)cnc12

InChI Key InChIKey=QDDLHFCNRILEHL-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450083   

TargetBeta-secretase 1(Human)
The City University of New York (Cuny)

Curated by ChEMBL
LigandPNGBDBM50450083(CHEMBL4166588)
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of BACE 1 (unknown origin) using 250 nM of Rh-EVNLDAEFK-Quencher as substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
The City University of New York (Cuny)

Curated by ChEMBL
LigandPNGBDBM50450083(CHEMBL4166588)
Affinity DataIC50: 4.20E+4nMAssay Description:Inhibition of BACE 1 (unknown origin) using 500 nM of Rh-EVNLDAEFK-Quencher as substrate after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed