BDBM50450176 CHEMBL4168778

SMILES [H][C@]12CCC(=C)[C@@H](C\C=C3/[C@@H](COC3=O)OC(C)=O)[C@]1(C)CCC(=O)[C@@]2(C)CO[Si](C)(C)C(C)(C)C

InChI Key InChIKey=SCPKTCVWVMYYAV-UHFFFAOYSA-N

Data  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50450176   

TargetSignal transducer and activator of transcription 3(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50450176(CHEMBL4168778)
Affinity DataEC50:  990nMAssay Description:Inhibition of IL-6 stimulated STAT3 activation in human AD293 cells incubated with IL-6 for 16 hrs followed by compound addition measured after 6 hrs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50450176(CHEMBL4168778)
Affinity DataEC50:  1.97E+3nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human AD293 cells incubated with IFNgamma for 16 hrs followed by compound addition measured aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50450176(CHEMBL4168778)
Affinity DataEC50:  4.43E+3nMAssay Description:Inhibition of IFNgamma-stimulated STAT3 activation in human HeLa cells incubated with IFNgamma for 16 hrs followed by compound addition measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50450176(CHEMBL4168778)
Affinity DataEC50:  4.57E+3nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human HeLa cells incubated with NF-kappaB for 16 hrs followed by compound addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Macau

Curated by ChEMBL
LigandPNGBDBM50450176(CHEMBL4168778)
Affinity DataEC50:  7.52E+3nMAssay Description:Inhibition of NF-kappaB stimulated STAT3 activation in human AD293 cells incubated with NF-kappaB for 16 hrs followed by compound addition measured a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed