BDBM50450310 CHEMBL4168336

SMILES CNC(=O)C1(CCCCC1)NC(=O)c1ccc(o1)-c1ccc(CSc2nc3CCCc3c(=O)[nH]2)c(F)c1

InChI Key InChIKey=LQPLCSWGMYVKEF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50450310   

TargetMatrix metalloproteinase-9(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50450310(CHEMBL4168336)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP9 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50450310(CHEMBL4168336)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP8 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
Target72 kDa type IV collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50450310(CHEMBL4168336)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP2 using fTHP-15 as substrate preincubated for 30 mins followed by substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMatrix metalloproteinase-14(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50450310(CHEMBL4168336)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP14 expressed in Escherichia coli using fTHP-15 as substrate preincubated for 30 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50450310(CHEMBL4168336)
Affinity DataIC50: 43nMAssay Description:Inhibition of recombinant human full length MMP13 expressed in mouse NS0 cells using fTHP-15 as substrate preincubated for 30 mins followed by substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Graz University of Technology

Curated by ChEMBL
LigandPNGBDBM50450310(CHEMBL4168336)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human MMP1 expressed in mouse NS0 cells using Knight substrate preincubated for 30 mins followed by substrate addition by f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed