BDBM50450470 CHEMBL4166574

SMILES Oc1ccc(c2cccnc12)S(=O)(=O)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=QZQSLHOKWGDYGA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50450470   

TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450470(CHEMBL4166574)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of c-terminal hexa-His tagged human S-COMT expressed in HEK293-6E cell membrane homogenate using 7,8-dihydroxy-4-methylcoumarin as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetLanosterol synthase(Rat)
Lieber Institute For Brain Development

Curated by ChEMBL
LigandPNGBDBM50450470(CHEMBL4166574)
Affinity DataIC50: 63nMAssay Description:Inhibition of c-terminal hexa-His tagged human MB-COMT expressed in HEK293 cell membrane homogenate using norepinephrine as substrate after 1 hr in p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed